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Answers to common questions about Xultophy® 100/3.6

About Xultophy® 100/3.6

What is Xultophy® 100/3.6?

Xultophy® 100/3.6 is an injectable medicine for adults with type 2 diabetes.

Xultophy® 100/3.6 is not for use in people with type 1 diabetes or people with diabetic ketoacidosis (increased ketones in the blood or urine).

How do I pronounce Xultophy® 100/3.6?

ZUL-to-fye is the correct pronunciation of Xultophy® 100/3.6.

What does the 100/3.6 represent in Xultophy® 100/3.6?

The 100/3.6 means that Xultophy® 100/3.6 is made up of 100 units/mL of insulin degludec and 3.6 mg/mL of liraglutide.

Do I have to take Xultophy® 100/3.6 at the same time every day?

You can take Xultophy® 100/3.6 at any time of the day, but you should take it at the same time each day.

If you miss a dose, take that dose at your next regular dosing time. Do not take an extra dose or increase the dose to make up for the one you missed.

Are there any interactions with other drugs?

Tell your health care provider about all medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Other medicines may interact with Xultophy® 100/3.6. See the Prescribing Information for more details.

Can Xultophy® 100/3.6 be used in combination with other diabetes drugs?

Xultophy® 100/3.6 is not recommended for use in combination with any other product containing liraglutide or another GLP-1 receptor agonist. It is not known if Xultophy® 100/3.6 can be used with mealtime insulin.

Other medicines also may interact with Xultophy® 100/3.6. See the Prescribing Information for more details.

How do I take Xultophy® 100/3.6 each day?

Your health care provider will give you your starting dose of Xultophy® 100/3.6 along with your blood sugar target range and show you how to adjust your dose based on your blood sugar readings. 

Use Xultophy® 100/3.6 exactly how your health care provider instructed.

How many times should I take Xultophy® 100/3.6 each day?

Xultophy® 100/3.6 is taken once daily, at the same time each day.

Will my dose of Xultophy® 100/3.6 change over time?

Your dose may change depending on your daily blood sugar levels.

Your health care provider will advise you on how to adjust your Xultophy® 100/3.6 dose based on your daily blood sugar readings.

Checking and tracking your blood sugar lets you and your health care provider know if your current treatment is working. 

Who can take Xultophy® 100/3.6?

Xultophy® 100/3.6 is approved for adults with type 2 diabetes.

How is Xultophy® 100/3.6 dispensed by a pharmacy?

The Xultophy® 100/3.6 pen is available from pharmacies in packs of 5. Each pen contains 300 units of Xultophy® 100/3.6.

About the Xultophy® 100/3.6 pen

What is the Xultophy® 100/3.6 pen?

Xultophy® 100/3.6 comes in a prefilled pen with no push-button extension. Doses can be adjusted in 1-unit increments.

What are the minimum and maximum doses that can be injected with the Xultophy® 100/3.6 pen?

The Xultophy® 100/3.6 pen can deliver 10 to 50 units in a single injection. Doses can be adjusted in 1-unit increments.

What does “no push-button extension” mean?

Other prefilled injection pens have a push button that extends when the dose is dialed up. The Xultophy® 100/3.6 pen has a spring-loaded mechanism that allows the push button to stay in place at any dose.

What needles can be used with the Xultophy® 100/3.6 pen?

The Xultophy® 100/3.6 pen is compatible with universal fit needles. We recommend NovoFine® and NovoFine® Plus needles, including NovoFine® Autocover®.

Does the Xultophy® 100/3.6 pen need to be refrigerated?

Your Xultophy® 100/3.6 pen can go for up to 3 weeks without needing to put it in a cooler or refrigerator.

Once I begin using a Xultophy® 100/3.6 pen, how long can I use the same pen?

Once in use, the Xultophy® 100/3.6 pen can be stored at room temperature (59°F to 86°F) or refrigerated at 36°F to 46°F for up to 21 days.

How do I discard the Xultophy® 100/3.6 pen?

Used needles and any empty Xultophy® 100/3.6 pens should be discarded in a sharps container or some type of hard plastic or metal container with a tight-fitting, puncture-resistant lid, such as an empty detergent bottle. Disposal requirements may vary locally. Check with your health care provider about the right way to throw away used needles.

Visit to find out how to request a sharps disposal container.

What if I have more questions about the Xultophy® 100/3.6 pen?

If you have any additional questions, ask your health care provider or call Novo Nordisk at 1-866-696-4086.

Xultophy® 100/3.6 support

How can I get more information about my diabetes care?

NovoCare® offers bite-sized, everyday lessons on eating better, moving more, and treating diabetes that you can learn in 5 minutes or less. Sign up to receive emails with tips for leading a healthier life and updates about Xultophy® 100/3.6. 

Sign up today.

How can I share my story of life with diabetes and success on Xultophy® 100/3.6 to help inspire other adults with type 2 diabetes?

Novo Nordisk partners with real adults to share real stories about life with diabetes. Please visit if you are an adult with type 2 diabetes and use Xultophy® 100/3.6 as a part of your diabetes care plan for blood sugar control and want to share your story to inspire others.

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